PUBLICATIONS
2009-2005
Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity
T. Puig, C. Turrado, B. Benhamú, H. Aguilar, J. Relat, S. Ortega-Gutiérrez, G. Casals, P.F. Marrero, A. Urruticoechea, D. Haro, M.L. López-Rodríguez, R. Colomer
Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity
R.A. Medina, J. Sallander, B. Benhamú, E. Porras, M. Campillo, L. Pardo, M.L. López-Rodríguez
Central nervous system (CNS)-related pathologies
M.L. López-Rodríguez
Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice
S. Ortega-Gutiérrez, D. Leung, S. Ficarro, E.C. Peters, B.F. Cravatt
The medicinal chemistry of agents targeting monoacylglycerol lipase
A. Viso, J.A. Cisneros, S. Ortega-Gutiérrez
Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase
J.A. Cisneros, S. Vandevoorde, S. Ortega-Gutiérrez, C. Paris, C.J. Fowler, M.L. López-Rodríguez
Structural models of class a G protein-coupled receptors as a tool for drug design: insights on transmembrane bundle plasticity
X. Deupi, N. Dölker, M.L. López-Rodríguez, M. Campillo, J.A. Ballesteros, L. Pardo
Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells
G.G. Muccioli, C. Xu, E. Odah, E. Cudaback, J.A. Cisneros, D.M. Lambert, M.L. López Rodríguez, S. Bajjalieh, N. Stella
Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions
E. de Lago, S. Ortega-Gutiérrez, J.A. Ramos, M.L. López Rodríguez, J. Fernández-Ruiz
The role of internal water molecules in the structure and function of the rhodopsin family of G protein-coupled receptors
L. Pardo, X. Deupi, N. Dölker, M.L. López-Rodríguez, M. Campillo
Synthesis of highly substituted enantiopure piperazines and ketopiperazines from vicinal N-sulfinyl diamines
A. Viso, R. Fernández de la Pradilla, A. Flores, A. García, M. Tortosa, M.L. López-Rodríguez
CB1 and CB2 cannabinoid receptor binding studies based on modeling and mutagenesis approaches
S. Ortega-Gutiérrez, M.L. López-Rodríguez
A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists.
M.L. López-Rodríguez, B. Benhamú, T. de la Fuente, A. Sanz, L. Pardo, M. Campillo
Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis.
S. Ortega-Gutiérrez, E. Molina-Holgado, A. Arévalo-Martín, F. Correa, A. Viso, M.L. López-Rodríguez, V. Di Marzo, C. Guaza
Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors
M.L. López-Rodríguez, M.J. Morcillo, E. Fernández, B. Benhamú, I. Tejada, D. Ayala, A. Viso, M. Campillo, L. Pardo, M. Delgado, J. Manzanares, J.A. Fuentes.
Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors
M. Delgado, A.G. Caicoya, V. Greciano, B. Benhamú, M.L. López-Rodríguez, M.S. Fernández-Alfonso, M.A. Pozo, J. Manzanares, J.A. Fuentes
Involvement of cannabinoids in cellular proliferation
M.L. López-Rodríguez, A. Viso, S. Ortega-Gutiérrez, I. Díaz-Laviada
Therapeutic perspectives of inhibitors of endocannabinoid degradation
S. Ortega-Gutiérrez
Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels
E. de Lago, S. Petrosino, M. Valenti, E. Morera, S. Ortega-Gutiérrez, J. Fernandez-Ruiz, V. Di Marzo
Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures
S. Ortega-Gutiérrez, E. Molina-Holgado, C. Guaza